Seborrheic alopecia is progressive hair loss on head and frontal areas. Seborrheic alopecia is a clinical common disease in dermatology. It is also one of refractory diseases. The disease impedes and affects face beauty. It often gives patients a great deal of mental stress and psychological burden.
The etiology and pathogenesis of seborrheic alopecia is complex. It is an androgen-dependent autosomal dominant multi-genetic alopecia. The genetic susceptibility and scalp hair follicles partial androgen metabolic abnormalities are the leading factors. Treatment of seborrheic hair loss is through inhibition of androgen metabolizing enzymes or the role of androgen receptors. It blocks androgen activity in the target organ expression.
There are some commonly used clinical medicines a synthetic finasteride group compounds is currently only approved for clinical 5a-reductase inhibitor, can specifically inhibit 5a-reductase type Ⅱ the same testosterone on the competitive enzyme binding sites, blocking testosterone conversion to DHT, thereby reducing the concentration of DHT in the blood, promote hair growth, so it is a specific competitive inhibitor of 5a-reductase type Ⅱ.
Minoxidil is currently the only approved listing non-prescription drug in the treatment of hair loss. The hair follicles in vitro experiments showed that minoxidil can promote hair growth is to stimulate the hair follicles, increase the proliferation and differentiation of hair follicle epithelial cells, promoting the growth of the hair follicle epithelium. Patients can buy minoxidil to stimulate the true dermal papilla cells overexpressing vascular endothelial growth factor gene transcription control raised the hair papilla cells on protein expression, thereby promoting hair growth.
Seborrheic alopecia belongs to hair moth hair loss in traditional Chinese medicine areas. Chinese medicine believes that hair growth depending upon the essence and blood, the liver stores blood, kidney essence, which in the hair, liver and kidney homologous blood and essence homologous kidney essence is blood to breed with each other, for a total of hair growth the necessary material. Liver and kidney deficiency type patients have a genetic predisposition, common in the mental or infirm, hair loss at the scalp smooth or left over from the sparse, soft, short hair, often accompanied by Yaoxisuanruan nocturia. Expelling nourishing liver and kidney, fill fine hair growth. Type in patients with leukemia hair orifices passionate blog depression, hair loss a long time. Expelling blood of plague, germinal. Commonly used drugs bupleurum, angelica, peony root, peach kernel, safflower, red sage root, motherwort, millettia and so on.
The relatively long time required for drug treatment of seborrheic alopecia due to hair growth characteristics and individual patient factors. Years of clinical observations suggest that most of the western medicine can only reduce hair loss and side effects are more pronounced; certain medications to promote hair regrowth but continue after stopping the hair loss makes its efficacy is difficult to maintain. Variety of Chinese medicine treatment of fat off, focus on treating the symptoms, regulate endocrine function on the whole, to achieve better clinical efficacy in improving symptoms, slow the course of the disease aspect. But cosmetic raw material suppliers have achieved breakthroughs on hair growth.
The treatment of seborrheic alopecia should adopt the combing treatment of traditional and modern medicine and the combination therapy of internal and external governance. It is necessary to attach importance to drug treatment. It also needs appropriate psychological treatment to eliminate neuropsychiatric incentives. Whine the patients need recommendations on diet to appropriately adjust the diets. With the three-pronged approach, it will improve efficacy and shorten the treatment course.
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