The health care function of wine

Wine contains a variety of nutrition: amino acid, protein, vitamin C - B1, B2 - B12 and the nutrition of grapes from natural ingredients and brewing process of ingredients can reduce cholesterol, prevent arteriosclerosis and heart vascular disease French people like to eat fatty foods, such as fat goose liver, but the French atherosclerosis and the prevalence of vascular disease in Europe countries lowest, this is due to the French wine. Can help digestion and promote metabolism. Drinking wine while eating can improve gastric acid content, promote human body in food calcium, magnesium, zinc and other absorption of mineral.

Wine is rich in phenolic substances, which have antioxidant effect, the prevention and control of degenerative diseases, such as aging, cataract, immune disorder and some cancers. With the advance of science and technology, with the instrument analysis precision degree of enhancement, the researchers can analyze more and more compositions in wines. In 1950 people can analyze wine only 50 kinds of component; 1986 can analyze 600 ingredients. Wine contains abundant nutritional ingredients, they mainly is all sorts of saccharide, organic acid kind, inorganic salts and trace elements, nitrogen material and a variety of amino acids, all sorts of vitamins. From the perspective of nutrition, wine itself contains rich nutrients, is a ideal nutritional drink wine. Not only that, some of red wine efficacy composition, have obvious health care function, red or the best health care sex drink wine. Red wine, has the health care function of many components, the most popular subject at present, is the resveratrol in red wine. resveratrol exist widely in nature plant body. Fine out in the eucalyptus, peanuts, tiger branches and more than 70 kinds of plants.

In the grape and grape juice, contains resveratrol, but the content is very low, in micrograms/liter order of magnitude, resveratrol manufacturer found that in the fermentation of grape juice, containing beta - glucose livor glucosidase, with fermentation process production of resveratrol reed alcohol quantity increase abruptly. High quality dry red wine, the content of resveratrol can reach 5 ~ 10 mg/L, from health care medical point of view, it have already with the therapeutic dose.

As one of pharmaceutical raw materials, resveratrol has a variety of health care and medical function, its main function is; (1) control atherosclerosis, coronary heart disease, ischemic heart disease and the role of hyperlipidemia. (2) has obvious antioxidant, clear free base, anti-aging effect. (3) antiplatelet aggregation, with the antithrombotic function. (4) resist cancer, inhibiting tumor and so on.

Source: http://www.cospcn.com

The effect of astaxanthin protect skin

Now skin protection had become the popular trend, whether minor or adults and even the elderly, are in whitening skin. So do you know as a Cosmetics material, how does astaxanthin work in skincare efficacy? Let us have a look.

First of all, astaxanthin have the effect of prevent you from the sunlight, it has unique molecular structure, the physical absorption peak is about 470 nm, is just like it’s the most perfect unique natural sunscreen, if in the outdoor it can rapid recovery from ultraviolet burn damage skin, astaxanthin is also the best products protect the human body skin from uv damage .

Secondly, astaxanthin can dispel spot and whitening skin, astaxanthin can effectively restrain the formation of melanin, and can significantly reduce melanin precipitation, let you can away from obscure blind spot skin, rather than spend a lot of money to beauty parlour to whitening skinor why not spent your money to buy astaxanthin health care products, can let you rest assured edible and won't have side effects and bad harm, astaxanthin’s whitening effect is more than many other  products. Astaxanthin capsule, there still did not find out any kinds of material which can have such a good prevent melanin precipitation effect in the same concentrations so far, so you can imagine how good it is, sometimes while doing mask we can also with a drop astaxanthin in the mask., insist to use astaxanthin capsule can achieve a very good effect.

What’s more, astaxanthin can also anti-wrinkle, our skin is comsist of the skin layer and the dermis and subcutaneous fat structure, the dermis contains collagen, elastin, and some other constitute which let our skin smooth and elastic, but these same element is also very easy to damage, and thus our skin also appeared wrinkles, the directly reason to prevent skin oxidized is not eat collagen, but edible astaxanthin, astaxanthin is the most strong antioxidant in all food, so if you want to prevent wrinkles just eat astaxanthin.

However where to get natural astaxanthin? The astaxanthin manufacturer tell us that the salmon contains one kind of powerful antioxidant components - astaxanthin. Salmon is the most effective in whitening  in all the deep sea fish. Because it contains unsaturated fatty acid in the moist skin, plays an important role in preventing and removing wrinkles. The unsaturated fatty acid is the skin barrier component, the supplement can help skin lock moisture, achieve moisturizing effect. In addition, it also has strong antioxidation, can effectively prevent skin aging and wrinkles, and the salmon contains the most aliphatic acid in all the fish. In the salmon there is another powerful antioxidant components astaxanthin, salmon orange red is derived from it. Astaxanthin’s ability of antioxidant is 550 ~ 1000 times than common vitamin E, can effectively combat free radicals, postpone skin aging, also can protect the skin from uv damage at the same time.

Source:http://www.cosprm.com

The Role of Biotin In The Glutamic Acid Fermentation

As a cosmetic raw material, biotin has important influence to glutamic acid biological synthesis methods. At present, the application of glutamic acid produce bacteria in industrial have glutamic acid corynebacterium, lactose fermentation short bacillus, scattered branches short bacillus, yellow short bacillus, bite ammonia short bacillus, etc.

The strains in common use in our country are Beijing rod rod bacteria, pure tooth corynebacterium, etc. Glutamic biosynthetic pathway is roughly by glycolysis of glucose (EMP approach) and hexose phosphate branch (HMP way) generation pyruvic acid, then oxidized to acetyl CoA (acetyl CoA), and then enter the Krebs cycle, generating alpha ketoglutarate. Alpha ketoglutarate in glutamate dehydrogenase catalytic and NH + 4 existence condition, generation glutamic acid. In the glutamic acid fermentation process, the influence factors of strains metabolic pathway. Glutamic acid produce bacteria need growth factor biotin. When biotin are lacking, strains grow very slowly, When biotin excess, the converted to lactic acid fermentation. Therefore, usually control the biotin in the moderate conditions, to get high yield of glutamic acid.

In the glutamic acid fermentation industry, corn steep liquor is an important source of biotin, also it is one way of biotin manufacturer produces biotin. But the composition of corn steep liquor different with the sources of the raw materials and processing methods. So the glutamic acid fermentation production process, corn pulp raw material should be decided according to the production condition.

In the glutamic acid fermentation, if it can change the permeability of cell membrane, make the glutamic acid row to cell outside continuously, it can get a lot of glutamic acid accumulation. Research shows that what affect the cell membrane permeability is the main factor in the cell membrane phosphatide content. Therefore, the produce of glutamic acid bacteria breeding, often from the control of the phospholipids in cell membranes of synthesis or damaged, such as biotin defect type strains breeding. Biotin is not saturated fatty acid synthesis process for acetyl CoA of CoA. Biotin defect type strains for not synthetic biotin, thus inhibiting the unsaturated fatty acid synthesis. And the unsaturated fatty acid is one of the components of phospholipids. Therefore, the synthesis of phospholipid quantity also reduced correspondingly, this would lead to cell membrane structure is complete, improve cell membrane to glutamic permeability. In fermentation process, the adjust and control of oxygen, temperature, pH and phosphate, etc are as follows: (1) the oxygen. Glutamic acid produce bacteria is aerobic bacteria, ventilation and mixing will influence not only strains source of nitrogen and carbon sources utilization,but also affect the synthesis of glutamate fermentation period and quantity. Especially the fermentation period, the increasing ventilation to glutamic acid synthesis. (2) the temperature. The growth of bacteria’s optimum temperature is 30 ~ 32 ℃. When bacteria growth to stationary phase, increasing temperature to produce acid, therefore, in the fermentation period, the temperature can be increased to 34 ~ 37 ℃. (3) pH. Glutamic acid bacteria fermentation produced the optimum pH in 7.0 ~ 8.0. But in the fermentation process, with the use of nutrients, metabolite accumulation, nutrient solution of pH changes continually. With the use of such as nitrogen source, release ammonia, pH will rise; When sugar is used generating organic acid, pH will decline. (4) phosphate. It is in the process of glutamic acid fermentation must be, but concentration too much, otherwise you will turn to valine fermentation. After the fermentation, commonly used ion exchange resin method of extraction. Glutamic acid in addition to used in the manufacture of monosodium glutamate outside, still can be used to treat neurasthenia and nutritional injection preparation, etc. Although the glutamic acid fermentation have greatly improved in quality and other aspects in China, but compare with the foreign advanced level, There are still exists a certain gap between compared. Mainly displays in: the old equipment, the scale is small, the automatic control level, the conversion and extraction efficiency is low, vulnerable to phage pollution, waste water pollution problem has not been fully resolved, etc.

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Application of Biological Technology In The Resveratrol Research

For the first time got resveratrol from wool leaf hellebore (VeYatYuD? Grandiflo - rtua) root in 1940. In 1960 Nonomura and other people come up with Res is some herbal medicine treatment of inflammation, lipid metabolism and heart disease of the effective components. In 1977, found in grapes Res as plant resistance to toxin exist. In 1989 WHO hold an epidemiological survey, the results show that the "French Paradox" (French Paradox), namely: high fat diet and coronary atherosclerosis low incidence was significantly consistency. Through further research, people found by drinking wine intake Res is French cardiovascular morbidity one of the main reasons for low: red wine for belt leather fermentation, peel and juice contact time long, make the skin a considerable amount of Res can enter the wine, which has good lipid peroxidation, known lipid peroxidation in atherosclerosis and other cardiovascular disease plays an important role. In 1992, the commercial wine found resveratrol the first time, the same year the academic circle further confirmed on wine rich in resveratrol. In recent years, many pharmaceutical raw materials suppliers learning function of resveratrol biological in deep research, these studies including lipid metabolism, arachidonic acid metabolism, etc., prove it has many important physiological activity, such as: cancer, protecting cardiovascular system, estrogen-like effect, influence bone metabolism, etc.

People to resveratrol natural resources have been studied extensively, at least has been in grape families, liliaceae, polygonaceae, leguminosae, myrtle, apiaceae, cyperaceae, palmae, buy a horse TengKe etc 21 families and genera and 72 species of plants found white hellebore alcohol. Its main exist in buckwheat fleece-flower root root, buckwheat giant knotweed roots, stems, grape family plant vitis peel, stone, liliaceous plant hellebore of roots, stems, leaves, leguminous plant groundnut roots, stems and the flowers. Especially in fresh grape skin of content is higher, about 50 ~ i00 > g/g, and with trans primarily. Grape cultivars, growth location, climate, planting technology, fungal infection degree and so on all affect the content of resveratrol. Made method to the influence of the content of resveratrol in grape wine was particularly remarkable, red wine the average contents of resveratrol to 4. 37 mg/L, and white wine only 0.68 mg/L. In improving content also had a lot of research, such as: use before harvest ultraviolet pulse radiation method improve the grape resveratrol content]; With recombinant yeast strain as a tool to improve the content of resveratrol in grape wine was white, natural including RS genes in plants suffer stimulation, can stimulate the gene transcription and translated into RS, then instantaneous synthesis of resveratrol. In grapes, peanuts, pine trees and other plants with induction type stilbene synthase gene expression mechanism, but most plant cells despite STS enzyme substrate, but lack of STS genes, and thus lack in the induced factor synthesis under the action of this kind of plant protection element ability.

Because the content of resveratrol in plants is very low, generally exist in glycosides. Many domestic scholars and resveratrol manufacturer are using chemical methods to make it. Generally speaking, chemical synthesis method with low cost, but from the food safety point, more and more scholars advocate getting it from natural plant extract, especially in foreign resveratrol biological extraction are more attention, and have a deep research.

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Plant extracts analysis of international market

Market of plant extracts is a developing market and has enormous growth potential, in 2005 the global market size of plant extracts at around 33 billion dollars, main plant extract suppliers are from India, and Brazil and China, United States, Asia, Europe is the world's third-largest market of plant extracts. According to United Nations estimates, annual industry growth rates between 10~20%.

Plant extracts export prices have been volatile, prices showed an upward trend in the early 1990s, the downward trend from 1996 later, from 1996 $ 20/kg down to 11.26/kg in 2003, a 40% decrease, from 2004 onwards, the price was stable and rapid rises, from $ 11.26/kg in 2003 rose to $ 19.12/kg in 2005, an increase of 68%, largely restored to the 1996 price level, especially in the Asian market recovery in prices faster, mainly due to the fast rising demand of the international market for natural medicines, another reason, China plant to industrial development for many years, as the international market to raise the threshold, their competitive capacity is also rising.

North American plant extracts more than 90 percent of the market depends on the United States, and the United States is the world's largest herbal market. According to statistics, each year in the United States to spend $ 6 billion for nutrition and health food, and this market is the increasing rate of nearly 20% per year. About 5% of patients taking natural medicines, of which 80% of the people taking traditional Chinese medicine in the treatment process. Plant extracts currently sold in the U.S. market may be divided into two categories: one is a standard extract usually extract such a clear and uniform quality standard system molecular biology research such as Ginkgo biloba extract (24% ginkgo flavonoids and 6% ginkgolide); other crude plant extract, such extracts are often only extraction ratio without a clear common standards, such as Equisetum extracts. Plant extracts accounted for more than 95% of the U.S. market for herbal medicines, raw herbs and other products account for less than 5%. In the last three years, Chinese exports to the U.S. plant extract 20-30% of the total export volume. The greater demand for varieties of Ginkgo biloba, Hypericum lotus Alice, soybeans, ginseng, etc.

Asian plant extracts market mainly Japan, South Korea and China, the current size of the market for about $ 3 billion, China accounted for 15%. Japan and South Korea are China's major exporting countries of the plant extract. Japan, South Korea, the source of plant extracts from traditional Chinese medicine, the last century 70's, Japan, South Korea vigorously develop Kampo and Korean medicine, Kampo and Korean medicine from Chinese medicine. Japan current pharmaceutical companies more than about 200. Japan Kampo formulations have more than 20,000 kinds of varieties. The majority of the pharmaceutical companies in Japan passed the GMP. The size of the Korean pharmaceutical ranked 10 in the world, the 80 pharmaceutical companies, accounting for 22.2% of the total number of Chinese and Western pharmaceutical companies. In developed countries, on the other hand, the production lines are gradually migrating to Asia, to promote the development of the Asian plant extracts industry.

Europe more prevalent as the raw material of herbal products, plant extracts, is currently the world's largest herbal medicine market, accounting for 45% of the global herbal medicine market, the market size of more than 10 billion U.S. dollars in 2005. Europe is the world's largest cosmetics and health food market and production research and development center. Since 1995, the European plant extract was relatively large market growth, most countries in more than 10% annual growth rate, individual countries or even as high as 16% (such as the United Kingdom, the Netherlands). Fastest growing herbal plant extracts into three categories: First, the role of preventive pharmaceutical raw materials, such as garlic, ginseng; medical institutions recognized the old products, such as the treatment of insomnia and neurological products; Third, is the discovery of a new treatment the role of the old products, such as evening primrose oil and ginkgo preparations. European governments and the academic community have a positive attitude on the plant extracts to strengthen the study of medicinal plants and traditional medicine, herbal ginkgo has been widely welcomed.

Source: http://www.cospcn.com

Astaxanthin is the most potent anti-aging foods

Although there is no one can live forever, and no one can stop what age left on the face, but we can retard the rate of aging, delay teh sking aging, wrinkles. In real life, there are many kinds of food can reach the effect, such as narural vitamin E, grape seed, β – carotene and so on, are good antioxidants, adequate intake per day you can achieve this effect. This is the one reason why people used it as cosmetic raw material and become more and more younger now.

In the fight against aging, and fight free radicals in the great war, people often say that those are not the most powerful, the most potent is astaxanthin. The word for perhaps many people unfamiliar, perhaps some people know, so let me introduce simple.  Astaxanthin is a red pigment, ornamental fish, salmon, shrimp and flamingo pink color can be given. Their chemical structure similar to the β-carotene. Astaxanthin is a carotenoid group. Highest level product is also carotenoids synthesis, beta-carotene, lutein, canthaxanthin, lycopene daily antioxidant, anticancer star only carotenoid synthesis intermediate, so in nature, astaxanthin has the strongest antioxidant activity against free radicals.

Someone will ask what is the free radicals. In general, radicals are the root causes of human aging and illness, the reason aging, physical deterioration, the skin loses its luster and flexibility, addition to age irresistible factors, the main too many free radicals in the body, the young man body better and the system to eliminate free radicals and reduce the harm it causes; However, with age, the body's ability to repair free radical decline; Failure to timely supplemental antioxidants, cell injury, disease arose, more and more evidence found by astaxanthin suppliers shows that the higher the content of free radicals in the body, the shorter the life.

Not only the presence of free radicals in the human body, but also from the outside of the body, such as smoking, car exhaust, then, there are two ways to reduce the free radicals harm: First, remove excess free radicals in the body, using the body's own free radical scavenging systems; The second is to explore exogenous antioxidants - radical detergent, blocking the invasion of free radicals on the human body, which is supplement can antioxidant foods, such as vitamin C, vitamin E, carotenoids and son on.

When body movement muscles will release free radicals, these radicals if not to be antioxidants in time, it will produce oxidative stress, resulting in muscle soreness or muscle tissue damage. Astaxanthin can act as an antioxidant to inhibit free radical oxidative damage to the body. Increase muscle strength and muscle endurance, alleviate sports fatigue quickly, reducing delayed muscle pain after strenuous exercise.

From the point of view of a healthy diet, away from the human food chain, the closer the food organisms containing astaxanthin astaxanthin content is lower, their food source is complex, the byproduct bring harm to human health (such as paragonimiasis more avian flu), food chain, the farther away from the human food organisms containing astaxanthin astaxanthin content, the higher, the more secure. So pure astaxanthin extracted from algae is the highest content of the safest food containing astaxanthin.

Source: http://www.cosprm.com

The health benefits of red wine and resveratrol

We all know that drinking a glass or two of red wine a day is good for health. In fact, that is true. For the Frenchman diet study found that, despite their daily food contains large amounts of animal fat and butter, but fat diet-related incidence of heart disease is not so high, which has a certain relationship with the hibit of drinking red wine. That is very similar to the asian one day one pack of igarettes but little risk of lung cancer. This phenomenon is also considered a puzzling thing. The study found that women drink a day, men drink two glasses of wine a day is safe intake.

Scientists believe that red wine contains resveratrol play the role of prevention of heart disease. In many research reports of resveratrol supplier have referred to the resveratrol effect, prevention of diseases other than heart disease, but also involving other diseases such as cancer and diabetes. In addition, anti-aging ability of this compound is higher than other nutrients. The following are several anti-aging mechanism: DNA damage. Human cells suffered millions of attacks every day, which will undoubtedly lead to DNA damage or an error, while resveratrol contribute to healthy cell regeneration. In addition, it can determine whether the cells need to be replaced as a gene regulator. The cell mitochondria to produce energy will die, resveratrol helps to provide more energy to produce more mitochondria. Resveratrol itself can affect the process of cellular senescence of the first three, but can not affect the fourth protein aging mechanism. Scientists has found that the polyphenol resveratrol mixed than they are individually more effective, and can have an impact on the fourth mechanism.  

However, some researchers believe that it needs to drink 100 glasses of red wine to play the anti-aging effect, unless drunk, otherwise it is impossible to reach this number. Therefore, resveratrol nutritional supplements are considered to be the only way to get the daily requirement. However, most of these nutritional content of only 50% purity, and therefore is not able to anti-aging truly effective way.  

Natural foods that contain resveratrol usually only provide a small amount of this antioxidant, a cup of boiled peanuts contain a maximum of 0.32 to 1.28mg of a glass of red wine provides fewer, only 0.25 and 1.25mg. The resveratrol content of grapes, berries and other plants. And all fruits and vegetables have different nutrients. You to read the vitamin content is purely average, the actual ingestion of food containing the nutrients may be less. Understand why plants contain antioxidants and similar compounds, they begin to close to the truth. These are the natural defenses of plants to produce these substances against bacteria or fungi, to prevent the sun's ultraviolet radiation, and even to resist insects. For example, tea, coffee and cocoa plant contains caffeine is a natural insecticide.  

Logically, if the plants are protected from disease and insect damage, they will produce less natural defense mechanism. This also is to contain resveratrol in food vary considerably in composition. It is the antioxidants of grapes and other plants used to combat fungal and bacterial infections. Many farmers have other means of protection of plants, especially for large farms. Resveratrol red wine from Spain typically contain the highest content of 145 grams of red wine is far from the same amount of peanut or grape content is high, only 0.29 and 1.89mg.  

The resveratrol as pharmaceutical raw material in the nutritional supplements is relatively high, this source of resveratrol whether can be normal absorpted of by blood is doubtful. The researchers tested for drinking after changes in blood in a glass of wine and the intake of nutritional supplements. In both cases, the amount of resveratrol in the blood did not change significantly. Some natural health advocates believe that people should eat more natural food to increase resveratrol, and avoid nutritional supplements. But most people rely solely on the diet, nutritional supplements, it is difficult to get all the vitamins and minerals. In addition, there are many chinese medicines and plant extracts help to maintain good health, prevent life-threatening diseases.  

Source: http://www.cospcn.com

Aloe vera and cosmetics

With strong stimulus in the outside world (such as microbial infection, trauma, exposure to antigen, etc.), skin will show the symptoms of swelling and pain medicine called inflammation. Humans as early as in thousands of years ago, recognized that anti-inflammatory effect of aloe. In recent years, experiments of tretinoin manufacturer prove to have a strong inhibitory effect of aloe on the antigenic and allergenic compounds induced histamine release, very effective for the treatment of acute contact allergy. International efficacy of products, Also specialized in aloe mucous mask as use cosmetics appear allergic reaction after the treatment product use.Therearelots of drugswith anti-allergic effects, such as adrenal corticosteroids (such as fluocinolone acetonide, dexamethasone), antihistamines (such as diphenhydramine, chlorpheniramine, etc.), these products with a variety of side effects  is prohibited used in cosmetics. But we can say that Aloe Vera is widely recognized as the safest natural allergy.  

The stain is a very tough enemy of the beauty industry and the medical profession . its causes is complex. In general, the main factor in the formation of stain is genetic factors, ultraviolet radiation, endocrine disorders, diseases and lifestyle issues and other factors, at the same time, the use of substandard cosmetics or skin care improper, will make dull complexion mottled. Somebody will say that  the  laser  can  clean sweep the stain ,but the laser destroyed only the epidermis into the pigment spots in the dermal layer of the words, it is not used. And laser makes skin damaged, so the stain will soon rebound and even cause inflammation stain . At present, whitening skin care products on the market more  used of additives, such as retinoic acid, tartaric acid, kojic acid, vitamin C, arbutin. Every skin whitening product has its own advantages and disadvantages, even if it is the latest whitening functional additives arbutin concentration in excess, it will also cause an increase in melanin. 

While in the cosmetics industry, the biggest headache is allergies. When the Allergy rate is too high, it will have a direct impact on products promotion, the impact of products market share, reduce the trust of the people to the brand. Allergenic cosmetics flavors, preservatives and active ingredients (such as lanolin, placenta extract, acid, retinoic acid, salicylic acid, etc.), which in turn are indispensable cosmetic raw materials, or reflect the cosmetics special effects and a selling point of the composition. Add allergy in high-end cosmetics, in order to reduce the allergy rate is undoubtedly the best choice, as allergy ingredients, aloe vera, of course is the first choice.  

People who ever contacted with aloe knows, aloe vera to all sorts of trauma, cuts and bruises, burns and scalds and insect sting injury, sun sunburn, can show good analgesic effect of healing. Modern medical research showed that as China's folk medicine has thousands of years history of the application of aloe vera, indeed has the very good wound healing effect. As for cosmetics, promote wound healing have special meaning: skin exposed, it is easy to damage by being exposed to the elements, etc, appear tiny wound. Dry rough, tarnished skin most often appear with tiny wound relevant. Aloe vera can accelerate tiny wound healing, can significantly improve the skin appearance, make the skin more delicate, soft, moist.  

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Status of chinese plant extracts industry

The plant extract industry is an intermediate industries, which are essentially within certain technical content of the pharmaceutical raw materials supply industry. Its development is mainly affected by the impact of the government's macroeconomic policy, the downstream product and international market changes. The current situation, these three aspects of the environmental factors are favorable in the main, which greatly promoted the development of the industry.   

In 2000 the Chinese government put forward the goal of modernization of traditional Chinese medicine, many listed companies have plant extracts as one of the raised funds. Injection of funds due to the intervention of the listed companies, to industry, at the same time into the technology and management, improve the industry as a whole size, equipment and technology to provide a solid foundation. On the other hand, 2000 had opened in Shenzhen GEM, as the emerging plant extracts, many companies use this opportunity to increase the scale of investment during this period, investment in research and the establishment of an international market, and entered the market counseling All these are conducive to the industry as a whole improved. China joined the WTO, the plant extract industry is to bring more market expansion opportunities.  

In 2005, the international pharmaceutical market growth rate of 9%, the herbal market was a rapidly rising trend, the market size of nearly $ 30 billion, about 40 million people use natural medicine, natural medicine sales have accounted for 30% of the global pharmaceutical market or more. Chinese health food into the 2004 trough, the rapid growth of more than 15%, the majority of the health food factory to build their own extraction plant, the main raw material provided by the extracts enterprises. Therefore, the international market demand for the rapid growth of the plant extracts market is extremely active.   

Asian plant extracts market grew rapidly in recent years, rapid development of Chinese herbs and oriental medicine, the demand for raw materials increases, stimulating the export of Chinese plant extract products. The United States is the country with the largest Chinese plant extract products export, despite the ephedrine export an annual growth rate of exports stable in more than 15%. Europe is the world's largest herbal market, accounting for 45% of the global share of greater than 25%, the growth rate of Chinese exports to Europe in recent years, the market has become a Chinese plant extracts most potential market.   

Although China claims to vast land, but in the plant extract industry in the early stages of development, Chinese companies at a low level of productivity, the harvesting of plant resources, while not considered long-term recycling plants, to take the destructive looting, coupled with on foreign companies to take low-cost predatory Chinese herbal medicine resources, some enterprises in the profit-driven, and even regardless of state laws, and serious damage to natural resources, such as Yunnan yew, Gansu, licorice, and Ephedra.  

The vast majority of plant extracts is limited by funding and regional restrictions, not be able to attract research talent, but also not to mention the establishment of R & D center; the other hand, laboratory and testing equipment behind, can not be applied in advanced extraction, separation, purification and drying technology, such as supercritical fluid extraction, membrane separation technology. The problems caused by the product technology content, corporate non-core products, which causes the lack of follow-up the momentum of development.   

In recent years, the international market attaches great importance to the pesticide and heavy metal residues in plant extracts, plant extracts or single herb preparations, should be of heavy metals is less than 5ppm, pesticide residues may not be detected, total bacterial count of less than 1000 / mg. From 2000 began to promote the planting of traditional Chinese medicine raw materials, according to the GAP standard, the plant extracts is not possible for all raw materials come from the GAP planting base. Pesticide and heavy metal residue has affected the plant extract products to international markets, especially the EU market.   

There is no uniform national or industry standards in plant extracts, although some plant extract suppliers formulate some standards, the majority companies do business base on the quality provisions in the contract, but the detection method of the product is a bit confused, which effect much the competition in the international market, and seriously hampered the industry development.  

Source: http://www.cospcn.com

Common side effects of astaxanthin

The most common side effects of astaxanthin is a harmless natural pigment changes, such as skin or stool color with a little orange. Whether humans or animals, even the intake of large doses, also no toxicant effect could be found. In addition, other less common side effects include decreased blood pressure and hormonal changes and so on.  

Astaxanthin is used by many as animal feed additives, it is also the crab, shrimp, lobster and salmon similar natural pigment of red orange. Astaxanthin is safe to use as animal feed nutrition practices, and most of the people eat seafood fed with astaxanthin will not flush any adverse reactions. Earlier in a dozen years ago, the United States food and Drug Administration took astaxanthin as human consumption of food to one of the ingredients.  

As a dietary product, astaxanthin has often been used as antioxidant to reduce cholesterol. Astaxanthin suppliers suggested astaxanthin in the treatment of carpal tunnel syndrome, arthritis, muscle injuries, diseases such as gastrointestinal discomfort and male infertility. However, it should be noted is that so far no sufficient scientific evidence to support these theories, and they can't prove that this nourishment is indeed a health effect.  

Common astaxanthin side effects including increased pigmentation, hair growth, hormonal changes and lower blood pressure. Sometimes gives rise to reduced calcium levels, such as low libido and male breast increase topic, but very rare. An allergic reaction is possible, and there is the great danger of proportionality. Persons allergic to this material fed with astaxanthin foods should be avoided. 

Astaxanthin and other drug interactions are also worth noting another subject. For example, the effect of antihypertensive drugs might increase due to ingestion of astaxanthin, and easily lead to dramatically reduce dangerous blood pressure. Hormone therapy and contraceptive effects can also be affected by the nutrition. In addition, the antihistamine drug and an asthma drug can also interact with astaxanthin reaction. Because clears of drugs in the blood from the liver enzymes will also be affected, thus resulting in increased residual drugs in the blood stream can.  

Astaxanthin and other health care products and herbal supplements interact reaction is possible as cosmetic raw material. For example, with the intake and saw palmetto, black cohosh and other drugs may affect hormone levels. Lower blood pressure side effects will also reduce calcium levels. In addition, β-carotene and lycopene and other carotenoids as antioxidants and astaxanthin with the intake will also reduce the absorption, so it is not recommended practice.  

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Resveratrol functions

Resveratrol is a compound found in many plants. It is also known as phytoalexin because plants can be naturally occurring antibacterial substances against bacteria and fungi. Plant containing resveratrol include grapes (grape skins), raspberries, mulberries, blueberries and cranberries, etc.. Peanuts, certain pine and Japanese Polygonum Weeds also contain resveratrol. Many people believe that resveratrol has anti-aging effect as pharmaceutical raw material, that some of the extracts from Polygonum cuspidatum market advertised as a nutritional supplement. But so far, the researchers conducted in mice, experimental data can only prove that resveratrol may have the effect of life-prolonging.

Resveratrol is considered to be the healthy one of the reasons is the observation of the French way of life. Although the French tend to have the fat diet, but their incidence of heart disease than most other countries. So many people think this is because the Frenchman the sake of the daily consumption of red wine habits. Have proved that red wine has anti-clotting effect, but many people believe that resveratrol has also played a role. In fact, very little content of resveratrol in red wine. If you want to get more resveratrol, the most common natural source of food should be peanuts. The peanuts are more than the number of berries or grapes to produce this compound.

A preliminary study by resveratrol supplier to determine resveratrol is a good antioxidant, helps to enhance endurance, and promote memory. Have some evidence to support this compound retroviral efficacy of prevention of HIV and herpes simplex point of view. It has also been advertised as a nutritional supplement due to anti-aging properties. The publicity may be a bit premature, not the negative impact of all such substances are found. Some studies have also found that resveratrol in the body to imitate the role of the human estrogen lead to the possibility of breast cancer.

However, compared to natural food sources, the actual amount of resveratrol nutritional supplements. Some studies suggest that food consumption can more than nutritional supplements were bioavailable. In addition, to supplement the content is far below the dose of mice, its human health effects is very small. But no matter what, this interesting plant compounds deserve further study. U.S. Food and Drug Administration has approved the addition of resveratrol as a drug investigation. Therefore, in the near future, the role of this substance will be more discoveries.

Source: http://www.cospcn.com

Function and metabolism of biotin

Biotin, also known as vitamin H, belongs to the class of B vitamins, is a water-soluble sulfur-containing vitamins. The natural state is colorless needle-like crystals, soluble in water and not soluble in ethanol, is quite stable at room temperature. It is necessary for the animal's body to maintain normal physiological function of low molecular weight organic compounds, animal indispensable nutrients. Biotin is widely distributed in plants and microorganisms in vivo, such as wheat, brewer's yeast, alfalfa, yellow corn, barley, wheat bran, whey powder, which the biotin content in the yeast with the highest utilization. In addition, the pig large intestine microbial synthesis of biotin.

Biotin have a certain effect on the cuticle to maintain hoof strength and hardness, and limb hoof keratin and hoof integrity. In pig production, the limb hoof disease is one of the sows are eliminated, the hoof keratin the cracks were caused by the swine limb hoof diseases. Biotin nutrient metabolism and hoof horny cracks related to biotin beneficial to the health of the mother trotters Ministry. Biotin also affect the reproductive performance of sows nest litter size, conception rate and estrus interval, biotin estrus interval can be shortened to improve sow litter size, and promote the formation of uterine expansion during pregnancy and the placenta, increasing the length of the uterine horn and placental surface area. The placenta is a filter between the maternal and fetal blood system, it can select the types and levels of nutrients through the placenta barrier, after implantation, fetal growth will be mainly dependent on this filtering role of the placenta to obtain nutrients. Biotin would be better for fetal nutrition, and promote the healthy development of the fetus.

In recent years, some studies by biotin supplier of biotin on growth of piglets and pigs growth, reported that biotin can improve pig weight gain and feed conversion rate. There were also reports that the diet supplemented with biotin can improve the carcass quality of fattening pigs and its mechanism of action is to reduce the body content of unsaturated fatty acids, thereby reducing the soft fat.

Natural biotin binding and free the two kinds of forms exist, the combined forms of biotin in the gut need to biotin-degrading enzyme decomposition before animal. Biotin by diet type and composition of the pig gastrointestinal absorption. Add crystalline biotin or diets containing higher levels of available biotin pig small intestine proximal main absorption site. According to test, inject biotin to the pig's large intestine, and found to be unable to improve the content of biotin in the blood, thus suggesting that the pig's large intestine microbial synthesis of biotin, but its absorption capacity is very low.

As the cofactor to many enzymes of the body, biotin plays an important role in maintaining metabolic dynamic equilibrium, so that it could be used as cosmetic raw material. The main function is involved in the body of carbohydrates, lipids, proteins and nucleic acid metabolism involved in the function of other nutrients, such as methyl transfer reactions and other metabolic processes, and lysozyme activation and sebaceous glands, as well as vitamin B6, folic acid, pantothenic acid metabolism are closely related. Biotin is absorbed by the body and distributed in body tissue, including the highest content of liver and kidney, related to the positioning of the intracellular distribution of biotin. When the animal absorption of biotin is higher than the storage capacity, the excess part of the urine.

Source: http://www.cosprm.com

China plant extracts industry overview

Plant extracts are using plants as raw materials, after extraction separation process of physical chemistry, gets to the concentration of one or more active ingredients in plants, without changing its structure and formation of effective components of the product. Plant extracts generally belongs to the intermediate product, current use is very widespread, mainly used in pharmaceuticals, health foods, such as tobacco, cosmetic raw materials or accessories. According to the plant's components are different, formation of glycosides, acid, polyphenols, polysaccharides, terpenes, flavonoids, alkaloids, etc; different in accordance with the final product characteristics, can be divided into vegetable oils, extracts, powder, lens, etc. China used to extract raw material plant of the species is also very much at present into the industrial extraction of plant varieties in more than 300.

Plant extracts currently take three main techniques: resin separation technology, industrial extraction and analysis of detection techniques. Technology already successfully applied in industrial decolorization resin extraction and separation, analysis of the protection of the environment, drugs, antibiotics, and other fields. Industrial extraction technologies including organic solvent extraction technologies. Analysis and detection technique criterion required composition and quantitative analysis of harmful substances, or with a standard control, or using a fingerprint for identification products, raw materials, production process and finished products are subject to strict testing. What technology and variety of plant extracts and extraction purposes directly related to the main organic solvent extraction technology of Chinese plant extract suppliers, subject to financial and technical strength take carbon dioxide supercritical fluid extraction and analysis and detection technique of smaller enterprises. Abroad is about more than 75% of Chinese herbs extracts for testing using HPLC, compared with 10.9% in Chinese Pharmacopoeia proprietary Chinese medicines containing the product.

70-90 's of the last century, Chinese medicine and food companies are equipped with plant extracts workshop, virtually no specialized plant extract enterprise in China. After 90, increased demand for herbal or natural medicine abroad, and has a wealth of plant resources in China, which naturally led the development of plant extracts industry in China. Initially rely mainly on raw material advantages, to provide rough products abroad, the original varieties of Ginkgo biloba extract, licorice extract, ephedra extract, green tea extracts. Up to now, plant extracts industry has formed a certain scale, over a total of more than 600 plant extract export enterprises in China, but most of the medicine and pharmaceutical raw materials suppliers or trading companies, production enterprises about more than more than 200, the scale and low skill levels, improving the lot of products, but mainly there is no technical content of products, with a certain few competitive products annual production value of more than 60 million Yuan enterprises. The whole industry less skilled, mainly exported raw materials at a low cost, very affected by the fluctuations of the international raw material markets, Chinese companies to cut prices in the international markets means lower competition, extracts of consequences is the international market for China's image is low-quality products, the purchase price is very low, China plants provide enterprises with low profit, greatly affecting the motive force of the development of planting industry in China. Plant extracts from general market demand in China accounted for about 5% of the plant extract sales, most of the product is sold in Europe, America and Japan, and Korea markets, Chinese plant extracts in the past two years annual growth rate is high, at around 30%, stripping out cost increase factors, extracts from plants in China in the coming years is expected growth rate of around 20%.

Source: http://www.cospcn.com

Brief introduction of biotin

Biotin, also known as vitamin H, coenzyme R. It is a sulfur-containing water-soluble vitamin, and is widely distributed in animal and plant tissues. Biotin also called biocytin, it is the carrier of carboxyl groups in the carboxylation reaction of many ATP. Animals lack of biotin can cause skin diseases and hair removal. Egg proteins contain biotin and avidin protein closely. So if you are eating a lot of raw eggs, can impede the absorption of biotin, so as to cause biotin deficiency. In normal cases, intestinal bacterial synthesis of biotin adequate human needs, symptoms of biotin deficiency does not occur.

Biotin is a water soluble sulfur-containing b vitamins, is related to the carbohydrate, protein and fat metabolism, Coenzyme a, also known as Coenzyme r. Biotin is a urea-based ring contains a sulfur atom and a valeric acid side chain, now known to have 8 types of isomers, only naturally occurring α-biotin, and biological activity. Biotin is a colorless acicular Crystal, easily soluble in water, slightly soluble in water, soluble in alcohol, but insoluble in organic solvents. On thermal stability, General cooking to be significant, strong acid, alkali and oxidizer can make their destructive, ultraviolet rays can also make its progressive destruction. Biotin in the body stored mainly in liver, concentration in the blood is low.

Biotin is of every living cell contain trace amounts of growth factors, is important for fat metabolism and carboxylation reaction Coenzyme is to maintain normal growth and development, essential for maintaining healthy skin and bone marrow of a nutrient. Research report by biotin manufacturer noted that biotin to treat baldness due to lack of biotin, improve the disadvantages of poor hair breakage, hair.

In 1901, Wildiers found a substance is required for yeast growth, he called this substance as "bioi". In 1933 when studying the growth of rhizobia isolated from beans, such as Allison, from which the isolation of a nitrogen-fixing bacteria, is named "Coenzyme r". In 1937, Hungary scientist Gyorgy discovered a substance to prevent adverse effects caused by egg white, this substance named vitamin h. 1940 Gyorgy and his colleagues through experimental research confirm that Coenzyme r, biotin, vitamin h, bioi are of the same substance, and to prove that a nutrient biotin is essential in mammals. In 1942, Vigneaud made the chemical structure of biotin. It is synthesized by biotin supplier in 1943.

Food mainly in the form of free biotin exists or in conjunction with protein. And protein binding of biotin in under the effect of protease, forming biocytin, biotin by intestinal enzymes, free biotin release. Biotin near end of the main part is absorbed by the small intestine. When low concentrations, absorbed by the carrier-mediated transport initiative; when the concentration is high. Is absorbed by simple diffusion. Absorption of biotin through the portal circulation, transported to storage within the liver, kidney, other cells that contain biotin, but less. Human intestinal bacteria can be from two replaced heptanoic acid nonanoic acid synthesis of biotin, but as the direct source of biotin is not enough. Biotin in the body primarily through urine discharge, breast discharge in biotin, but the amount is very small.

Source: http://www.cosprm.com

Chia seed's eating experience

Chia seed is considered to be "Indian long-distance food". And the warriors of the ancient Aztecs feed on the chia seed when in battle. I am a runner, and I consumption of chia seed to enhance stamina and endurance running in the mountains, and hang on for several hours several times. And this is the chia seed's initial function.

The 100g Hungariana promoter contains calories is 490kcal (light work of adult males need 10030kcal /day, light work of adult women need 8800kcal / day ). This shows, the daily intake of 1.5kg chia seeds/day will not get fat! The chia seed promoter contains a very high dietary fiber, 9.8 times that of rice, oats 2.6 times, 1.6 times that of wheat. Chia seed inside the cellulose absorbent function, after absorbing water volume will inflate larger. Thus, the secretion of fluid and the volume of cellulose will account for a large space in the gastrointestinal tract, enhanced satiety to the brain to convey " I'm full " message, and don't want to eat any more to achieve the purpose of control appetite.

Mixed with a tablespoon chia seed with a glass of water for 30 minutes, not only the volume swells and becomes chia seed sub-gel. This gel formation due to the soluble fiber in chia seed. The researchers believe that foods containing soluble fiber into the stomach can also occur to the same gel reaction. In this way, the gel into the stomach chia seed between its own carbohydrates and gastric secretion of digestive juice produced a physical barrier, delaying carbohydrate degradation monosaccharide digestion process, the body continues to provide energy.

Chia seed is also rich in omega-3 polyunsaturated fatty acids, it can not only lowering blood pressure can also fight against cardiovascular disease, eliminate inflammation, fight cancer, fight diabetes, the fight against neurological diseases and brain development. Omega-3 fatty acids or a way to protect the skin collagen biologically active substances, studies by chia seed supplier have shown each week to eat three times with Omega-3 food can delay the aging of the skin. Moreover, the sub-Hungariana rich in a variety of antioxidants, protease inhibitors (Pis), chlorogenic acid, caffeic acid, myricetin, quercetin, kaempferol flavonols, vitamin C, vitamin E, beta-carotene (vitamin A), selenium, etc., which can be an effective solution to skin aging, pigmentation, resistance to aging.

Omega-3 DHA, EPA has an important role in the oxygen-carrying blood, coagulation, endocrine, skin cell nutrition, nerve cell growth, for a variety of organ metabolism must. However, the body itself can not synthesize Omega-3, therefore necessary to supplement the food. chia seed in the Omega-3 polyunsaturated fatty acids and fish oil content is higher, and no heavy metal pollution. Do not have to manually add any anti-oxidant ingredients, we can guarantee one of the Omega-3 unsaturated fatty acid is oxidized.

This pharmaceutical raw material can be in any cooking recipes to replace the fat bad for your health. You can use uncooked seeds do salad sauce, dinner dishes, fruit and cream. You can also add them to cookies, cakes, muffins and other baked foods. I often add a few spoons in the fruit juice and water, and drink directly.

Source: http://www.cospcn.com

The principle of the glutathione whitening skin

Three amino acids in the formation of glutathione, it is a small molecule in the body. Each cell of the body containing these amino acid products. The body's immune system benefits enormously from the glutathione.We can take use watermelons, asparagus and other fresh vegetables and meat to produce the amino caids in cell. Glutathione in addition to these effects, but also can whiten skin color safely and effectively.

If you pay attention to the photos of top models’ childhood, you will find the color of their skin dark a lot than it is now. As a mild whitening ingredient, glutathione is an integral part of the skin whitening pills. It can reduce the appearance of the skin color, making it the best skin whitening solutions. All cells of the body can work more effective because of the existence of glutathione.

As the modern human pays great attention of the appearance,the demand of glutathione pills is growing more and more. Pressure, anxiety, and environmental pollution give the skin adversely affected. In addition, the pollutants in the atmosphere will lead to dull skin and delicate texture. Therefore, skin care has become a hot topic of public concern. This is why the skin whitening cosmetics materials can be popular solutions.

These glutathione drugs are given through the mouth following the doctor’s prescription, but many people still have a query on its security. However, the drug is safe which is confirmed after a series of clinical studies, because amino acids are the key ingredient for skin whitening agents. In addition, glutathione supplements can be used as antioxidants to strengthen the immune system. It contains vitamin C can make the skin smooth, flawless and wrinkle.

There are many false advertising about skin whitening products on the market. But glutathione suppliers are convinced that consumer glutathione pills is 100 percent secure, they do not contain any bleaching agents or chemical substances, from any perspective, these products will not do harm to human health.

Source: http://www.cosprm.com

Plant extracts industry development

Recent export performance of plant extract products is particularly in traditional chinese medicine products, and it is the most rapid development of such products, especially in 2011. For example, the export value of plant extracts is $ 1.13 billion, an increase of 47.0%; export volume of 42,000 tons, an increase of 14.9%; the average export price of 26.8 U.S. dollars/kg, an increase of 28.2% can be described as the volume and price both increase.  

In addition, the import growth rate of the plant extract is also very obvious that 2011 plant extracts imports amounted to $ 220,000,000, an increase of 67.8%; imports 1.8 million tons, an increase of 59.4%; the average import price of $ 12.4/kg, an increase of 5.2%. Which the essential oils of peppermint oil and other imports from Central Asia and licorice extract in resource scarce plant extracts as pharmaceutical raw material, and the import growth rate of more than 100%.  

Basically stable from the monthly statistics, the monthly import and export of plant extracts, plant extracts in December a single month import and export amount and number of ups and downs of little change; but the amount and number of year-on-year, imports rose significantly year on year, while exports rose more gentle.

As far as the market, China plant products export market is relatively stable, United States, and Japan, and Germany, and France, has been planting products major market. In recent years, Mexico, and India imports large quantities of Chinese plant products, dominated by pigment product. 2011 plant extract export markets except Latin America slightly tighten outside, other continents showed a more substantial growth in exports and export volume. In Asia, Europe and North America are still major areas of China's export of plant extracts, 2011 exports to the three parts of 82.6% per cent of China's total export of plant extracts. 

Asian markets: China plant extract exports to the Asian region was $ 440 million, accounting for 39.4 percent, exports grew by 18.8%. Among them, Japan and the ASEAN region based on Kampo is the major export markets in Asia. 

European market: the 2011 European plant extracts market trends strongly. As the world's largest herbal medicine market, the plant extract based products much local consumers. In December, the plant extracts in China exports to the EU for $ 290 million, an increase of 63.2 percent, export volume was 11,000 tons, an increase of 15.1 percent, the average export price increased by 41.8%, volume and price go up a good situation. The main exporters of plant extracts in Europe is Spain, Germany, France and Britain.

U.S. market: the North American market or the U.S. market is the Chinese plant extracts of the most important export market, since 2005, has been ranked the location of the plant extract export. Taking dietary supplements habits of most Americans, which also spawned the growth of the world's largest dietary supplement market demand for the plant extracts. The U.S. market has become a global pharmaceutical and healthcare plant extracts vane, increase or decrease in market demand will have a direct impact to the rest of the world market changes. 2011, the plant extracts in China exports to the U.S. $ 180 million, an increase of 54%; export volume of 8050 tons, an increase of 32%.

With the development of plant extract products, the number of chinese plant extract suppliers is also growing. The record of them is 1402 (excluding production and sales of classes ) in 2011. Among them, the private enterprise is the main force in the export of plant extracts, which exports accounted for more than 56%; exports of foreign-funded enterprises accounted for 32% and state-owned enterprises accounted for only 11% of the total exports. In 2011, the plant extract prior to export 10 enterprises exports accounted for 33%, the top 10 barriers to entry increased from $ 16,140,000 to $ 22,190,000. A slight increase of the overall industry.

Source: http://www.cospcn.com

Antioxidant activity of astaxanthin

Oxidative damage to the organism is mainly manifested in the destruction of lipids, proteins and nucleic acids. Lipid due to the destruction of the free radical chain reaction, resulting in biofilm structure and function change; protein oxidation is very sensitive, especially the sulfur amino acid; bases and pentose in DNA molecules are easily oxidized position, the oxidation can lead to DNA breaks, base degradation and protein cross-linking, making the genetic material to mutate or cause cell death.

Carotenoids by physical quenching Singlet oxygen, singlet-oxygen additional energy transfer to carotenoid, carotenoids accept energy into triplet (3Car3), then release the extra energy through exothermic go to the ground state (1Car), which is a physical process, the structure of the carotenoid is not changed, you can continue to quench singlet oxygen. The speed of chemical reaction can be used to describe the rate constant (k), the faster the reaction, the greater the rate constant. Carotenoid quencher of singlet oxygen, the speed can be described by the rate constant (kq) kq value of carotenoids reflect the size of the potential effectiveness of its antioxidant activity, kq, higher the value, the faster the reaction with singlet oxygen carotenoids to quench singlet oxygen, kq, higher the value, the more a certain amount of carotenoids per unit time, quenching singlet oxygen;, of course, values ​​of kq, and experimental conditions (such as temperature, solvent, photosensitizer types, determination methods) are closely related, so the size of the kq value of more carotenoids, the experimental conditions must be the same.

It can be seen from the data of carotenoids singlet oxygen quenching ability and its number of conjugated double bonds, and the end of the ionone ring is not obvious. 4, 4 'carbonyl (astaxanthin and angular zeaxanthin) can improve the ability to quench singlet oxygen the astaxanthin quenching singlet oxygen capacity of the strongest, 100 times that of the α2 tocopherol, and glutathione the reaction rate of 1/125 of α2 tocopherol, but in vivo environment and experimental conditions very different from the results of chemical experiments by astaxanthin supplier does not reflect the real situation in vivo; In order to simulate the biological environment, people with liposomes, cultured cells and animal experiments, the results due to the antioxidant capacity of oxidant species in biological environments, and the interaction between the different other substances such as carotenoids in the lipid environment (such as biofilms) than water-soluble antioxidants (alpha lipoic acid, glutathione), antioxidant capacity, while the latter antioxidant in the cytoplasm plays an important role.

Astaxanthin is a widely used carotenoid as cosmetic raw material, people have been extensively studied for its antioxidant and anti-oxidation efficiency. Several carotenoids quenching singlet oxygen, the efficiency of blood cells in vitro study found that lycopene is the most effective, astaxanthin, followed by, β2 carotene worst. Astaxanthin clear that the efficiency of free radicals and angular zeaxanthin, 50% higher than the β2-carotene and zeaxanthin, clear hydrogen peroxide free radicals and prevent lipid peroxidation was significantly better than zeaxanthin, canthaxanthin, and β2 carrots. Antioxidant, astaxanthin, each individual is not the strongest, but the highest antioxidant capacity. Astaxanthin similar to vitamin E, fat-soluble antioxidant in the performance of excellent oxidation resistance of biofilm and lipid-rich tissues. Feed with vitamin E deficiency, vitamin E rich feed and w (astaxanthin prime) = 1% of the feed fed to mice two to four months, and then liver mitochondria and red blood cells in vitro antioxidant experiments, found that astaxanthin significant antioxidant activity, more effective than vitamin E.

Source: http://www.cosprm.com

Red wine and heath

Along with the increasingly popularize of healthy life, red wine has becomed the tendency of world's consumption of alcohol. More and more fashional people and leader trend to taste  red wine, enjoy the healthy life which is brought by the red wine.

It is well known that the red wine can make beauty. But not all the red wine can reach the effect. The resveratrol in the red wine is the real one that can make beauty which has the antioxidant function. This is a good component to condition the skin from the inside and outside. Resveratrol, has found by resveratrol supplier in 72 kinds of plants, including mulberries, peanuts and other particularly high content of grapes,especially the highest content of high-quality red wine.

Resveratrol is a plant origin of estrogen, senile osteoporosis, acne and so there is a clear preventive effect. In addition, resveratrol also has anti-bacterial, anti-inflammatory, antithrombotic, anti- allergy effects, and atherosclerosis sclerosis, ischemic heart disease, hyperlipidemia, and others have a significant preventive effect, retard aging. The latest research shows that resveratrol can fight against fat, food help you lose weight. Resveratrol content of high and low, often become an important basis of the difference between enterprise technology level of indicators to measure the merits of red wine quality.

Red wine also contains a wonderful pharmaceutical raw material - tannins. Tannin changes with exposure to air after the rich, level change, brings surprise completely unpredictable. Good red wine due to the selection of advanced oak aging for more than 18 months, the extraction of oak within the rich tannic substances, making the wine structure to fuller, more full-bodied texture. This wonderful tannins prevent tooth decay and prevent radiation against a lot of good, and can increase the contraction of smooth muscle fibers in the intestinal muscular system, have a certain effect on the colitis.

Other nutrients in red wine are also very rich, and play a very important role in promoting human health, is better than a lot of health care products. For example, red wine contains sugar, pectin, alcohols, organic acids, inorganic substances, trace elements and dozens of amino acids and a variety of vitamins. Now known to about 600 kinds of useful elements on the human body, of which there are many substances not found in other foods. Red wine contains a lot of glucose and fructose, not only can be directly absorbed by the body but also the role of the yeast directly fermented into alcohol and carbon dioxide. The alcohol content in red wine, good health, the body's cellular respiration, can promote blood circulation and promote healthy and beautiful.

A growing number of studies have shown that red wine can almost be called the perfect "health drinks" in the "green" "low carbon" concept prevalent today, the red wine also is met with "healthy" and "quality" by more and more people to accept and loved.

Source: http://www.cospcn.com

Market application of Vitamin H

Vitamin H, also known as biotin, a water-soluble B vitamins. Vitamin H is the body's fat metabolism and other important coenzyme of the reaction of carboxylic group, is also a livestock growth and development essential to a biological catalyst. It mainly used for medicine, nutritional additives, feed additives. In recent years the international market demand, its prices are also soaring, once reached more than 3000 U.S. dollars per kilogram of high-priced.

Vitamin H in the feed additive, medicine and health, cosmetic raw material products and beverages has a wide range of applications. Especially for feed additives, currently most of the global vitamin H production is used in this regard. Previous years, the world market for vitamin H, has been little demand. Europe, North America and Japan, Korea and other developed countries are processed into animal bones, viscera, and other additives added to the beverage, these items contain natural vitamin H, and thus without additional plus vitamin H. European "mad cow" incident, it was found that the cause of the BSE is animal bone meal, offal and other substances are added to the feed. Since then, Europe and the United States and other developed countries have abandoned animal bone meal, offal, switch to the chemical synthesis of a variety of vitamins as feed additives for some time even supply, prices are also rising. And foreign distribution to goods often require the manufacturer to issue a certificate, to confirm that vitamin H is indeed the chemical synthesis production, not the natural items extracted.

The amount of Vitamin H on the Chinese market is not that much, and mostly used in medicine and hygiene. A few years ago, Chinese medicine with vitamin H per year are imported from abroad, imports about 1-1.5 tons per year. Such as a pharmaceutical company in Japan in May 1998 allowed to export to China of vitamin pharmaceutical raw materials, specifications for iron cans into each to listen 100g, 500g, 1 kg, 5 kg , four kinds of packaging.

In contrast, vitamin H is rarely used in feed additives in china by biotin supplier. In the long term, as China's rapid economic development, the 1.3 billion people's living standards continue to improve, demand for meat, poultry, eggs and other food will last, a large increase. According to statistics, China 's feed annual output of about 50 million tons, per kilogram of feed add 0.15μg vitamin calculation, it needs vitamin H 7.5 t. Now feed for more than 30 years possession kilograms per capita in China, Japan, 200 kg, 300 kg in Western Europe. If it reachs the level of developed countries, China's market feed additives only vitamin h per year up to 50 to 70 tons. It can budget, vitamin h in the Chinese market in the future development of space is very great.

Source: http://www.cosprm.com