In clinical practice, the doctors often use the topical retinoid drugs combining with other therapies to treat psoriasis. Retinoid drugs’ topically use combining with other treatment methods can reduce doses of the drug. In the first use, people should choose 0.05% topical retinoic acid concentration or mix it with equal parts of Vaseline. And then gradually increase the dose of tazarotene to make local skin gradually adapt it . it will reduce the sensitivity.
Topical tretinion can be effective treatment for mild to moderate psoriasis drugs, creams and gels (0.05%, 0.1%), two types of the drug compared with other topical treatments compared to the day, only topical once, and the gel is more meet the beauty needs. Typically, the patient only at night the surface of the rash daub a small amount of drugs, scalp, and nails can be used. With temporary irritation due to the drug, it generally can not be used in the eye and around the genitals, gel each time you use can not exceed 20% of body surface area, while the cream is not more than 35% (and refers to the palm of your hand accounting for body the surface area of l %).
The topically use of cosmetic raw material tretinoin in combination with other treatment methods can reduce the dose of drug. In the first use, you should select topical retinoic acid concentration of 0.05% or mixed with equal amount of Vaseline, and then gradually increase the dose of retinoic acid to the local skin to gradually adapt to the lower sensitivity. It should be noted that the use of the drug, although sometimes the redness of the skin, but in fact the rash is improved and becomes thinning.
Slow effect of retinoic acid from the efficient topical glucocorticoids, usually three months to use up to 70% remission of clinical multi-joint (glucocorticoid + retinoic acid) to increase the therapeutic effect, reduce the retinoic acid-induced local irritation, to extend the duration of remission and reduce the side effects of glucocorticoids. In some cases, combined with UVB phototherapy in order to achieve better outcomes, and reduce their drug dosage. There are no significant phototoxicity occurs.
Adverse reactions of topical retinoic acid are burning and itching. It usually happens among 20% to 40% of patients. And therefore the doctors need to inform patients before the use of biotin. Due to its possible teratogenic effects, pregnant women and women of childbearing age should avoid to use it. The site that using the biotin drugs should avoid the El and cannot use the sunscreen.
Source:http://www.cosprm.com
