2012年9月19日星期三

The detoxification role of glutathione

Glutathione is a small peptides compound of three amino acids, as an important anti-oxidant and free radical scavenger in body, such as in combination with free radicals, heavy metals, etc, make the harmful poisons turn into harmless substances in body and excreted out of body. Glutathione is now been widely recognized as a whitening ingredients in the international market, mainly by blocking the of tyrosinase synthesis of melanin pathway to inhibit melanin production, so as to achieve the whitening effect. Glutathione’s whitening effect is significant, in recent years it has also been widely used as cosmetics material.
Glutathione is a tripeptide combine of glutamic acid, cysteine ​​and glycine, mercapto group-containing, has detoxification of anti-oxidation and integration. The mercapto group on the cysteine ​​glutathione active group (glutathione often abbreviated as G-SH), easy has integrated detoxification with certain drugs (such as paracetamol), a toxin (such as free radicals, iodoacetic acid, mustard, The combination of lead, mercury, arsenic and other heavy metals). Therefore glutathione (especially glutathione in liver cells) can be involved in the biotransformation, and thus the machine body of harmful poisons into harmless substances, and excreted. Glutathione also helps to maintain normal immune system function.
Glutathione not only removes the body of free radicals, but also can improve the body's immune system. The glutathione in maintaining health, anti-aging, the efficacy of cells in slow elderly play better than the young. Glutathione also can protect the hemoglobin not to be oxidated by oxidation hydroxide radicals and other oxidation so that it continued normal functioning of the ability to transport oxygen. Part of hemoglobin in red blood cells under the action of hydrogen peroxide and other oxidants, the oxidation of ferrous iron to ferric iron to make hemoglobin into methemoglobin, losing the aerobic capacity. Glutathione can directly in combination with an oxidizing agent such as hydrogen peroxide, to generate water and oxidized glutathione, but also be able to methemoglobin reduction is hemoglobin. The content of glutathione in human erythrocyte is high, it has important implications for protecting the red blood cell membrane protein thiol in a reduced state and preventing hemolytic.
Glutathione to protect the enzyme molecules in the-SH group, is beneficial for the enzyme activity play its role, and can restore the activity of the-SH group which has been damaged by the enzyme molecule, to resume the enzyme activity. Glutathione can also inhibit ethanol against fatty liver. Glutathione a strong protective effect for the leukopenia symptoms caused by radiation, radioactive drugs. And enter the body of toxic compounds, heavy metal ions or carcinogen glutathione and promote excreted, play a role in detoxification.
The glutathione manufacturers remind that taking glutathione seldom show up nausea, vomiting and headache, rare rash. Glutathione couldn’t use in allergy, and shall not be used in combination with vitamin B12, menadione, Calcium Pantothenate, orotic acid, anti-histamine preparations, sulfa drugs and tetracycline and so on.
Source:http://www.cosprm.com

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