Know minoxidil clearly

Minoxidil was originally a drug used to treat hypertension in the 1970s. It is classified as a potassium channel opener and has the effect of peripheral vascular expansion. Study of this potassium channel openers has been done for many years. Minoxidil is the only drug that is extensive used in the human body. Hirsutism, hair or non-expected growth was originally the side effects of this drug. But because of inspiration of this side effect, minoxidil is imported for the treatment of male and female’s androgenetic alopecia. Today, the minoxidil has been developed into two forms. Oral minoxidil is used to treat high blood pressure and topical minoxidil is used in the treatment of hair loss and baldness.

Through the stump-tailed macaque’ experiments, it is confirmed that minoxidil can be shortened hair follicle telogen. It makes hair follicles enter into early stationary growth phase, histological study shows that in these primates, minoxidil does to increase a certain percentage of hair follicles into the growing season and reduce the number of telogen hair follicles; can also increase the size of the hair follicle itself, so that hair becomes more coarse. In human trials, minoxidil for hair growth cycle have the same effect, increasing hair diameter is also possible to happen.

Minoxidil does not inhibit the function of male hormones in the animal body, minoxidil does not stimulate testosterone or adrenal androgen secretion; on human experimentation, the serum testosterone concentration is not will change because of the use of minoxidil). However, according to the results of clinical trials, with the hair of male pattern baldness hair loss in men and women re-use of minoxidil in hair quantity and weight were significantly increased. Minoxidil allows tiny hair follicles to produce a reversal of the role of renewable and let minoxidil accelerate growth and promote the key into the growing hair follicles from the telogen. If cosmetic raw material minoxidil is resolved to vasodilators, it has the function to increase blood flow and stimulate hair growth results.

The compositions of skin are from outside to inside. There are mainly three parts of the epidermis, dermis and subcutaneous tissue. The epidermis is the outermost layer, the thickness is only about 0.5mm. It is mainly composed of layers keratinocytes. Keratinocytes can protect the body from intrusion by the external environment or micro-organisms. It maintains a certain humidity and moisture. It has been confirmed that, minoxidil has a certain effect for the growth of keratinocytes, primate and human hair regeneration. For germinal effects, usually 6-8 weeks after the use of minoxidil products, patients can begin to see the increase of hair. And after 12-16 weeks, people can see noticeable results. But not everyone is applicable to the above effective period. Sometimes the hair loss increased. And the increasing hair is not always growing in coarse types. It is likely to grow finer hair.

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