Eat peppers can ease chest and belly cold pain in winter

In human’s impression, the spicy food may be harmful to human health. However, according to the latest study pointed out that these harmful food in people’s stereotype, in fact may produce considerable help to human body, every hectogram pepper content vitamin C up to 198 mg, ranking first in vegetables. Vitamin B, carotene, calcium, iron and other mineral also have rich content. Medical experts believe that peppers can ease the chest and belly cold pain, stop diarrhea, inhibit intra-abdominal parasites, control of heart disease and coronary artery disease; can stimulate oral mucosa, causing gastric peristalsis, promote saliva secretion, increase appetite, promote digestion. Spicy products because of its sterilization, preservation, seasoning, nutritional, and fend off the cold and other functions, played a positive role in human disease prevention, medical treatment, genetic improvement and promoting human evolution. Therefore, add a little pepper in the winter daily recipes, have a great benefit to the health of the body. The chili is the master of antioxidant, has always been considered to stimulate food pepper, in fact, contains a very high antioxidant content, and the content even 42 times than apple, 12 times than oranges, and four times than grapes, is a very good anti-aging medicine. pharmaceutical raw materials suppliers said, in fact, every kind of spice or pepper are contain a certain effect.

Pepper slimming effect, the reasons why people can not refuse the pepper is that: burn fat, Slim plastic body. The key to burning fat chili is that the capsaicin, the role of capsaicin is to stimulate the body produce heat, speed up metabolism. Fast heat systems can improve the efficiency of the body, like the fast-running machines can consume large amounts of hydrocarbon fuels. After eating a meal of spicy, can consume more than 25% of calories. When hot, drink a cup of caffeine-rich black tea in the belly burning, the effect is even more obvious. The chili can promote the production of two enzymes in the body, in the process of burning fat, they can convince the fat cells side unloading, while preventing excessive accumulation of fat. This way to lose weight without any diet rules companion, the capsaicin stimulates production of endorphins and serotonin, at the same time will allow you to have a good mood.

Pepper can prevent heart disease, the chili can promote blood circulation, increase the flexibility of blood vessels, reduce the risk of hardening of the arteries, help prevent cardiovascular disease. Pepper content rich of vitamin C, have the effect of antioxidant, while enhancing the body’s resistance also anti-aging. Special reminder by capsaicin manufacturer: chili should not eat too much. Due to the pepper heat is toxic, excessive eating can make the body wet from the heat, manifested as skin acne, high blood pressure, hemorrhoids increased, epistaxis and so on. If eat lots of chili for a long time will cause poisoning performance, such as epigastric burning sensation, abdominal distension, abdominal pain, nausea, vomiting, dizziness, and even vomiting blood, blood in the urine, high blood pressure or decline.

Source:http://www.cospcn.com

The extensive application of glutathione

According to the study of glutathione manufacturer, glutathione as one of the most important antioxidants in body, can directly through for H + antagonistic toxicity of oxygen free radicals, remove the superoxide ions and other radicals in body, to prevent damage to the liver cells.

The pharmacological effects of glutathione: reduced glutathione is a tripeptide composed of glutamic acid, cystine and glycine, it is a cofactor of glyceraldehyde dehydrogenase, also the coenzyme of ethanediyl aldehyde enzymes and triosephosphate dehydrogenase which can involve in the in vivo TCA cycle and glucose metabolism, make the body get the high energy. Glutathione can activate a variety of enzymes, such as the body’s mercapto group (-SH) enzyme, coenzyme, etc. thereby contributing to the carbohydrate, fat and protein metabolism, and can also affect the metabolic processes of the cells, is an intracellular important regulator of metabolic substances.

In addition, glutathione in the body exist in two forms of reduced glutathione and oxidized glutathione, its active ingredient is glutathione, can participate in vivo redox processes. Under the action of glutathione transferase, glutathione can combine with the peroxides and free radicals to anti oxidants destruct mercapto, protection of cell membrane protein containing a mercapto group and a mercapto group-containing enzyme is not destruction against free radical damage to vital organs. Reduced glutathione is widespread in the animal and plant’s cells, and content in the liver and lens more. Now can be produced by chemical synthesis or fermentation.

Reduced glutathione is cofactor of glyceraldehyde phosphate dehydrogenase and the coenzyme of glyoxal enzymes triosephosphate dehydrogenase, involved in the body of the citric acid cycle and glucose metabolism, make the body get high energy. Can activate and protect a variety of enzymes, such as sulfhydryl (-SH), in vivo cholinesterase enzyme, so that the body against iodoacetic acid, mustard gas, free radicals (such as superoxide anion), heavy metals (such as mercury, lead), poisoned epoxide and other harmful substances, thereby contributing to the carbohydrate, fat and protein metabolism, can also affect the cell's metabolic processes. Promote eye tissue metabolism, inhibit crystal protein thiols instability, prevent the development of cataracts and retinal disease, which can be used to keratitis, corneal trauma. These diseases before reaching old age, began regular use of such antioxidants can play a preventive role. There are also good increasing role in vision.

Glutathione suitable for a variety of liver diseases, especially alcoholism, liver disease, drug-induced liver disease (including anti-cancer drugs, anti-tuberculosis drugs, neuropsychiatric drugs, antidepressants, acetaminophen and Chinese medicine) positive effect on the infectious liver disease - hepatitis B, chronic active hepatitis C also improved the symptoms, signs, and recovery of liver function. Used for poisoning rescue for heavy metals, organic solvents. Prevention and treatment of radiation injury, leukopenia disease and radiation-induced bone marrow tissue inflammation. It can also be used as cosmetic raw materials, used for facial pigmentation, sweat stain and a variety of causes pigmentation. For eye drops to treat early age-related cataracts, can also be used for corneal ulcers, corneal epithelial peeling, keratitis.

After the reduced glutathione treatment, it may cause rash, stomach pain, nausea, vomiting, injection of local mild pain. A small number of patients using the drug drops may occur itching, irritation, ocular hyperemia, blurred vision and other symptoms, after drug withdrawal it will disappear.

Source:http://www.cosprm.com

Capsaicin can make of antidote and tear gas

Ordinary people feel the more red chili the more spicy, but purified capsaicin is white! In fact, the red is capsanthin, it is not spicy, the extracted pigment can added to foods. The capsaicin manufacturer said that capsaicin purification is very difficult, previously only can purified to about 10%, and now after years of research, it has been improved. Preparation of capsaicin is a very complex process, star the pepper acquired from the market to become white crystalline capsaicin, even if the various steps incessantly row to do should spend a day. Capsaicin extract, first of all should shatter the pepper, screen pepper seeds, then ground into powder, made of granules, last adding to an organic solvent to extract, all in all it by the various extracts, separated manners to get this crystalline.

According to the content of capsaicin, 1 kg of capsaicin needs at least 34 pounds of pepper extract. At present, many scientists are researching red dried chili, because this type of pepper can both extract capsaicin and capsanthin. High purity capsaicin should not touch the skin, it will burn skin. The studies show that if the capsaicin accidentally gets on the hands, wash your hands many times will still feel hot and pain. Because capsaicin belongs to lactam substances, it will burn the skin.

Capsaicin is an extremely spicy vanilla amide alkaloids, it is the main source of chili has a spicy flavor and drug function. Capsaicin is white crystals, melting at 65 ° C to 66 ° C; soluble in methanol, ethanol, acetone, chloroform, benzene and ether, and soluble in alkaline aqueous solution, produce irritating gases at high temperatures. Natural capsaicin composed by a series of congeners: capsaicin, dihydro-capsaicin, drop dihydro capsaicin, high dihydro capsaicin, capsaicin and so on, the most important of which is capsaicin, dihydro-capsaicin.

The application of capsaicin, medical treatment, weight loss and make drug rehabilitation tear gas: as far as I know the use of capsaicin is very extensive. The high purity of capsaicin has many physiological activities, such as capsaicin can be used for biological and chemical pesticides, sprayed it on the plant’s leaves, neck, fruit and flowers can be effectively expelled aphids, spiders, leaf-eating insects and fleas; capsaicin can also used as pharmaceutical raw materials, these drugs can be used for analgesia and treat skin diseases, arthritis, etc; in addition, capsaicin can also be used to do the diet food, even for giving up drug. Capsaicin also have a very wide range of uses in other areas. For example, capsaicin can be used to produce functional coatings, coated in a shell of the ship to prevent the adhesion of algae and marine life, coating the surface of the cable and wood can also prevent rats chewing on. In addition, many of the tear gas is also made of capsaicin, which is that it can as a function of defensive weapons materials.

Source:http://www.cospcn.com

Astaxanthin can inhibit acute inflammation

Natural astaxanthin can regulate the immune response, inhibit the growth of cancer cells, reduce bacterial infection and gastritis, against oxidative damage induced by ultraviolet ray. Everyday life, we will be more or less show up some physical illness, small to fever and big to cancer as well as hard-to-cure diseases. As the saying goes: Blocked have means to resist. We will do this by taking drugs to treat these diseases. However, how many people will get to know the real reason why you will be sick ? For example, you catch a cold, you are just thought the weather was cold yesterday, you wear less clothes. You did not expect to find the root cause of the disease, enabling to prevent the occurrence of disease in advance, rather than when the disease was occured, and then spend money on medicines to treat it.

Rely on oxygen, our body is full of vitality. We breathe in oxygen, and use it to burn fuel (food consumption) and produce energy. However, when cells use oxygen waste produced as a by-product - in the form of high-energy oxygen molecules. These reactive oxygen molecules have a name, called free radicals. Free radical damage to human tissue and cell structure, such damage called oxidative stress - the body utilize oxygen to impose their own pressure.

Most of the aging-related health problems, such as wrinkles, heart disease and Alzheimer's disease are related about the oxidative stress. As the cosmetic raw material supplier noted: "Few people can live up to their potential maximum life span. They often die of various diseases earlier, including a large part of radical initiator." Despite those research results have been half a century ago, but people understand these concepts until recently.

In fact, almost all the organs of the body are very susceptible to hurt by oxidative stress, there are numerous symptoms, such as fatigue, general weakness, muscle and joint pain, indigestion, anxiety, depression, pruritus, headache, and difficulty concentrating and hard to cure infection. The most common diseases induced by elevated levels of oxidative stress are heart disease, cancer, osteoarthritis, rheumatoid arthritis, diabetes, and neurodegenerative disorders such as Alzheimer's, Parkinson's disease.

We also found that oxidative stress and inflammation are closely linked. In body’s everywhere, as long as there is one phenomenon there will be another phenomenon attendant. Take the example of the lungs of smokers, the existence of a large number of oxidative stress in the region. The smoke is an oxidant, with a high oxidative capacity. When inhaled this oxidized tobacco, lung tissue damage occurs, quickly causing inflammation. Therefore, smokers are mostly suffering from bronchitis.

Astaxanthin is a super natural extracellular antioxidants first separated from the lobster in 1938. according to the surveys by astaxanthin suppliers, it is the only antioxidants can retard aging function of organs and tissues. It can clear excess of free radicals in the body to reduce oxidative stress, thereby enhancing our body's immune function, prevention of inflammation and disease occurrence.

Source:http://www.cosprm.com

The modern production and applications of chili

Capsanthin is both pharmaceutical raw materials and cosmetic raw material, in industrial, it commonly used ethanol or n-hexane extract of red pigment from the red chili powder, due to the complex chili ingredients, low solvent selectivity, the purity of the product obtained and spicy, smell, so it must be approved by de-spicy, deodorized refined before use. Because of capsanthin oily characteristic makes the removal of residual solvent in the product is difficult to reach the required standard, it greatly affect its use and export.

In recent years, a high-tech industrial application of the separation technology - supercritical fluid extraction to solve these problems. Carbon dioxide is the most common solvent in the supercritical fluid technology, its critical temperature is 31.05C, SCFE technology operation can achieved at around room temperature, in order to save energy, and its critical pressure is not very high. Processing equipment is not difficult. Most of its solute having greater solubility, while the solubility of water in the carbon dioxide was small. Carbon dioxide also has a non-combustible, non-toxic, chemical safety, cheap and easy to get the advantages. Using SCFE-CO2 can be directly extracted no spicy ingredients, odor component and yellow pigment-free taste of the high capsanthin from chili.

The impact of the extraction conditions to extract: the lower the pressure, the smaller the color value extract, mainly because of pepper pigment solubility less than spicy ingredient in chili oil resin, fatty acids and Triglycerides.

The application of modern biotechnology in enhance capsaicin, capsaicin was crystallized in the water as a white monoclinic rectangular plate crystals, crystallized in petroleum ether is scaly. Soluble in alcohol, ether, benzene, chloroform, fats and alkaline aqueous solution. High temperatures produce irritating vapors.

Capsaicinoids have been widely used in the pharmaceutical industry and the food industry. The different pepper varieties contained the different amount of capsaicinoids, differences generally dried chili 0.2% -2% capsaicin matter content, have an important role to improve the chili quality and value.

The capsaicinoids belongs lactam compounds composed of vanilla amine and branched lipid intestinal acid. Vanilla base amine part derived from phenylalanine. Because of capsaicin synthetic phenolic precursors - coumaric acid, phenylalanine, cinnamic acid, caffeic acid, vanillin synthetic precursor of the protein, alkaloids, flavonoids, and lignin, therefore pepper biosynthesis to the existence of the problem of competition with other biosynthetic pathways Community. Through metabolic regulation or gene regulation best to promote the biosynthesis of capsaicin. It is of great significance to the industrial production of capsaicin.

The enzymes involved in the capsaicinoid biosynthesis pathway have: phenylalanine lyase, cinnamic acid hydrolase, coumaric acid hydrolysis enzymes, capsaicin synthase is capsaicin last enzyme in the synthesis process, is a critical the rate-limiting enzyme. Of capsaicin synthase gene cloning, the use of genetic engineering and modern biotechnology prompted capsaicin synthase gene expression in pepper fruit and plant cell culture fully screened the high capsaicin prominent body, excellent cultivating transgenic yield capsaicin content of pepper varieties, will greatly improve pepper quality, which will effectively promote capsaicin industrial development. Source:http://www.cospcn.com

The side effects of topical vitamin A acid in the treatment of acne

Usually skin disease acne is common among adolescents, can be significantly improved by treatment, several mainstream drug treatments including isotretinoin and antibiotic treatment, and other cosmetic skin care products for acne often contain hormone ingredients which harmful to the human body.

Use vitamin A acid to treat acne will cause a lot of side effects: topical vitamin A acid, which is derived from vitamin A acid topical formulations. Main ingredients include Vitamin A acid, isotretinoin, adapalene, the major role is to increase the metabolism of the cells of the epidermis, make keratosis abnormal situation can be improved, the anti-inflammatory response, regulating the growth and differentiation of epidermal cells, promote collagen production, improve sebaceous gland function, reverse photoaging, inhibit melanin generation, promote thickening of the dermis layer, the treatment of acne. Of course the vitamin A acid can cure the acne, but vitamin A acid is a drug that contains the ingredients of skin irritation, also have a lot of side effects. Vitamin A acid promote angiogenesis, the outermost layer of horny slightly thinner. If patients redness of the skin, should be used it carefully. Its skin irritation is larger, thin skin, or even run out will cause part of the exfoliation.

The cosmetic raw material suppliers remind that vitamin A acid has two sides, has both advantages and disadvantages, and must not blindly use. Especially pregnant women must be used with caution. A new study found that the drug must be used under the guidance of a doctor, pregnant women can not use this drug, because the drug can cause birth defects of the baby. And retinoic acid-related drugs pregnant women should be banned.

Scientists do a small study show that pregnant women used retinoic acid appeared habitual abortion or born infants have serious defects. The study found that people can easily buy the retinoic acid. And tretinoin manufacturer do not follow the standard drug dose.

In addition, in order to be effective in preventing the occurrence of acne, except for drugs, you should pay attention to the conditioning of everyday life, including eating less animal fat, high-sugar, spicy, fried food, avoid liquor, coffee and other stimulating drinks, eat more vegetables fruit and light food, drink more water; regular cleaning of the skin with warm water or sulfur soap wash the affected area, but do not use too irritating soap, do not use oily cosmetics. Recurrence or worsening of acne is often associated with mood swings, etc., should maintain ease of mind, eliminate stress, anxiety, worry, ensure adequate rest and sleep; do more exercise, prompting the body's waste excreted in a timely manner, the skin constantly sweating keep pores open in the process, and then promptly cleaned.

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Depth development outlook of chili

According to the effective ingredients of chili can develop all kinds of peppers emerging products.

1. Pain and topical agents: chili can be made into ointment for cold pain, skin reflex from the local blood vessels dilate, promoting strong local blood circulation, so it has the effect of removing stasis and lee joints. Topical use can cure rheumatoid arthritis.

2. Drug treatment analgesics: as pharmaceutical raw materials, the medical effects of capsaicin, recently received a lot of special attention. The scientists found that capsaicin does not produce drug dependence of neurological drugs, has a powerful drug and analgesic efficacy. Use high purity capsaicin to make of the injection of the drug treatment is a broad-spectrum efficient new drugs, in drug treatment has a powerful role for almost all drug addiction, so it has a broad space for development, the analgesic injection made with capsaicin for the massive trauma, produced by advanced cancer pain has a strong blocking effect. The analgesic efficacy and heroin considerable, but it does not produce the drugs dependence like heroin.

3. As a digestive drugs: pepper can stimulate the oral mucosa, increase the movement of the stomach naturely, increasing the activity of digestive enzymes, which promote appetite, and improve digestion.

4. Natural red pigment: With the constant discovery of synthetic pigment toxicity, countries in the world to use synthetic pigment varieties dwindling, the use of non-toxic harmless natural materials to extract food coloring has become an inevitable trend. Prohibit the use of chemical pigment agreement signed with the EU countries, capsanthin has been the product of choice as a red pigment.

Pure capsanthin is a deep rouge red needle-like crystals are naturally exist in the four terpene natural pigment of ripe red pepper fruit, which polar red component is capsanthin and Capsorubin of (Capsorubin) is 50% -60% of the total, and the other is the polarity tiny yellow components, the main component of the B-carotene (B-Carotene), the zeaxanthin (Zenxanlthin), and pepper flavin (Crytoxanthin ), they are with vitamin A activity. Capsanthin not only bright colors, good thermal stability, safe and reliable, and can be widely used in the pharmaceutical industry, such as tablets coated coloring. Health drugs, cosmetics and so on.

5. Natural preservative

Pepper pericarp contained capsaicin and other substances can inhibit many bacteria, as a natural preservative, safer than chemical synthesis of anti-corrosion and have nutritious.

The studies by capsaicin supplier shows: capsaicin have strong inhibition of Staphylococcus aureus, Escherichia coli, Bacillus subtilis, yeast, Hansenula, Aspergillus niger have to prove that it can not suppress the bacteria can inhibit fungal. Therefore, the chili is a broad-spectrum antibacterial material. Fresh pepper because of its low cost, high yield, is the extraction of natural preservatives have a good raw material, developed for the food industry preservatives. Not only with good economic but also have social benefits of healthy, green, environmental protection. It has been reported that capsaicin strong inhibition of Bacillus cereus and Bacillus subtilis, but the effect is lighter to Staphylococcus aureus and Escherichia coli.

6. Slimming and beauty drugs: chili can improve the capacity of fat metabolism, the role of the liquid solution fat to achieve weight loss goals.

7. Natural antioxidants: the body's disease, aging, is closely related to the restore and oxidation imbalance in the body, in recent years, the rapid development on the research and development of anti-oxidants, its related chemically synthesized antioxidants is severely restricted source. The natural antioxidants in plants has caused great concern.

The chili has a strong antioxidant capacity, mainly due to polyphenols and vitamins contained in the pepper pericarp.

Source:http://www.cospcn.com