2013年4月17日星期三

Market breakthrough of astaxanthin

Astaxanthin is still a new thing, low market awareness: the customers were generally never heard of this product, and easily misunderstood this product, thinking that this product is shrimp, or something extracted from the shrimp, people also not very familiar with Haematococcus pluvialis, it is very trouble to explain. Today the antioxidant products on the market are many and complex: like Q10, OPC, VE, lycopene and so on, astaxanthin how to compared with the antioxidant products sold in the existing market and highlights the features, it is necessary to carry out a large number of science publicity to raise consumer’s awareness of astaxanthin, and catch the astaxanthin for two populations of eye disease, age-related macular degeneration, cataracts and cardiovascular disease to highlight the breakthrough.
Start astaxanthin new markets should pay attention to several aspects: 1. new customers were more difficult to accept it (especially for the astaxanthin suppliers that have more products variety), this is a normal phenomenon. But this kind of astaxanthin supplier can through other products to transform new customers, through the service, and then grafted to astaxanthin; 2. there are some customers think that the price is too high, this situation can be used to solve in two ways: first, take the original purchase of customers’ other products to equivalent exchange to reduce the difficulty of increasing astaxanthin taking customer base; establish the psychological orientation from the beginning to customers that "astaxanthin is the most powerful antioxidants in the world, is truly worthy of the high-end products", so it's value to be expensive, expensive justified. 3. since the astaxanthin had been promoted in the market, many customers reflect that the product in the treatment of eye diseases, stable blood pressure have good results. As long as developing a new customer conversion strategy, have a large number of qualified astaxanthin that certified by customers, as well as the emergence of similar products in the market, there are still some potential. 4. popularize health education, change people's concepts of health is more important than promote their products. The first is educating the sales team, everyone must master the antioxidant knowledge, in order to be confident, skilled services for consumers; followed by is the customer education, do well the health education. As long as well done the education, sales will be successful. There are many mature markets, as long as new markets actively involved in Company linkage, the start of market, the number is just a matter of time.
Astaxanthin is a carotenoid. There are a lot of well-known stars in the carotenoid family, such as beta-carotene, lutein, lycopene and so on, these carotenoids are good nutrients, can improve our life’s quality and prolong life. However, astaxanthin is the most benefit one in the family. Natural astaxanthin exists in some organisms such as algae, fungi, as well as shrimp and crab, salmon, their surface will show a beautiful orange or red, those red substances were astaxanthin.
Scientific studies have shown that astaxanthin has a multifaceted role of scavenging free radicals, anti-inflammatory, protecting blood vessels, reducing cholesterol, whitening skin, wrinkle-free, ease joint pain, improving immunity. In addition, astaxanthin in preventing cancer, protect eyesight, protect the nervous system, prevent Alzheimer also have a satisfactory effect. At present, the world’s commercial use astaxanthin has synthetic, natural extracts. The former are generally used as feed nutrition enhancer, the latter is commonly used in human nutrition and health care products and cosmetic raw material.
Source:http://www.cosprm.com

2013年4月12日星期五

New pesticides to control cotton bollworm



New insecticides developed in recent years, such as macrolide emamectin benzoate and spinosad, insect growth inhibitor hexaflumuron, chlorfluazuron, methoxyfenozide are has good control effect on cotton bollworm.
Bioassay results show that spinosad products have obvious ovicides effect on cotton bollworm; emamectin benzoate, spinosad, chlorpyrifos, lambda-cyhalothrin, phoxim, profenofos, efficient cypermethrin on eggs hatch has significant inhibited effect; emamectin benzoate, lambda-cyhalothrin, spinosad, chlorpyrifos, beta-cypermethrin, profenofos and phoxim have better poisoning effect on bollworm’s young, old larvae; insect growth regulator to the newly hatched larvae of cotton bollworm have obvious growth inhibitory effect. Field experiments showed that emamectin benzoate, lambda-cyhalothrin, profenofos, wherein the control effect of lambda-cyhalothrin is fast and efficient, the effect of spinosad and methoxyfenozide is slower, less effective.
Although chlorpyrifos’ toxicity is moderate, phoxim with less toxicity, and both were have good prevention and treatment effect on cotton bollworm’s larvae, but because of it belongs to high toxic pesticides to bees, fish, trichogramma, so that in field trials do not choose these two agents. Although lambda-cyhalothrin, beta-cypermethrin, profenofos be used for preventing and controlling cotton bollworm in the field for a longer time, but they still have good control effect; emamectin benzoate is a new macrolide compound, with efficient and ultra-efficient characteristics on certain pests and harmful mites, the main mode of action is stomach toxicity and tag out, its mechanism of action is to interfere with the pest neurophysiological activity, inhibitγ-amino butyric acid receptor chloride ion stream, blocking the movement neural information transmit, make the motor nerve palsyed, the insect stop feeding and death, has a strong osmosis on blade, kill pests under the epidermis, and have long duration. The test confirmed that after emamectin benzoate treating bollworm eggs, the effect on bollworm egg shell’s early larvae is the best, and both have good effect on bollworm’s young, old larvae, is an ideal bollworm control agents, this result is the same with other studies.
Spinosad is a microbial metabolite, belongs to low toxicity, broad-spectrum pesticides, biodegradable in the environment, do not pollute the environment, to lepidopteran pests have fast contact and stomach poison effect, with strong osmosis on blade, can kill pests under epidermis, longer duration, to some certain pests have ovicides effect. The study found that spinosad does have a toxic effect on bollworm eggs, and after treatment the newly hatched larvae’s mortality is high, but the effect of spinosad to young and old larvae is slower.
Methoxyfenozide is a low toxicity, dihydrazide insect growth regulator, belonging the molting hormone analogues, able to simulate the function of Lepidoptera larvae molting hormone, to promote it molting, mature early, incomplete development, this pesticide have little effect on other insects except Lepidoptera, with a long duration, stable, low toxicity, efficient, safe for people and livestock and other features, it is the ideal selective insecticides in comprehensive prevention and control. The results show that although methoxyfenozide to the newly hatched larvae of cotton bollworm have significantly inhibited effect, but the effect is slow, and its field trials were less effective.
Source:http://www.cospcn.com

Methods of dermatologists cure acne



In general, dermatology does not encourage to press the affected area, because improper handling will make the inflammation problem intensifying, and will lead to deeper inflammation of hair follicles, form acne. Generally speaking, acne treatment can be divided into two major categories of oral and topical: oral antibiotics can prevent the growth of bacteria in the hair follicles which cause inflammation, thereby reducing acne; some oral vitamin A will control skin cell renew and reduce oil secretion, but will also comes with dry skin side effects, these patients can choose some with moisturizing auxiliary treatment products. Tretinoin (Vitamin A series) can effectively get rid of acne, it is reported that: tretinoin (Vitamin A series) remove acne, cosmetic effect is significantly, from remove acne, smooth fine lines, dilute the stain to narrow pores, almost almighty. Because of these drugs are irritating, many patients often abandon the use. The researchers point out, learn how to proper use tretinoin can reduce the side effects.
Compared to prescription products, the efficacy of non-prescription tretinoin product is weak, the onset time is longer, but to skin is relatively mild, and the price is relatively low. Therefore, the tretinoin manufacturer recommend that sensitive skin and first time users should be selected concentration of 0.1% of non-prescription tretinoin formulations retinol, it can be slowly converted to the active ingredient - tretinoin, so that its irritating to the skin will relatively small.
If use three months, the skin has not improved, we can consider switching to more effective prescription preparations. In this case, the non-prescription products had been make the skin gradually adapt to, so that even change to the preparations at this time, the side effects produced by latter will likely be significantly reduced. Due to tretinoin drugs will in some extents dry the skin. Therefore, choose to start using in summer when the air humidity is relatively large, it is a more scientific program.
What should be noted that during application period of retinoic acid, should be suspended for the depth of facial care. Because dry skin is more prone to having burning sensation, it is necessary to consider continuing facial cares after the stimulation symptoms of tretinoin disappeared completely. Moreover, some facial products, including scrub cream, exfoliating products, containing alcoholic toner, containing drugs cleanser and cosmetics, may react to tretinoin, should avoid using at the same time.
Cosmetic raw material suppliers advise that when the first time use tretinoin, take the size of the beans amount to try, but should avoid applied in lips, eyelids, and other sensitive areas. Retinoic acid has obvious teratogenic effects, even if apply very small doses, or a very short time, it may cause fetal severe brain and heart defects, mental retardation, therefore, during the treatment and stopping medicate 30 days after should strict contraception. Due to retinoic acid can make the surface dead skin shedding, which is equivalent to remove the natural protection of skin against UV layer. User can topical use the antioxidant products which can reduce inflammation, such as green tea essence. Mixed with oats and fresh milk into a paste, applied to the face for 10-15 minutes, first wash with warm water, then the cold water, it also can remove steatorrhea material, make the skin smooth and delicate.
Source:http://www.cosprm.com

2013年4月1日星期一

The nature and application of spinosad



The pure spinosad is a white or grayish white solid crystallized, with a similar slight odor of stale soil, is the mixture of 85% - 88% spinosad component A and 12% - 15% spinosad compound D. Spinosad is not soluble in water, soluble in organic solvents, such as methanol, ethanol, acetonitrile, acetone, dimethyl sulfoxide and dimethylformamide, etc. In aqueous solution, pH is 7.74, to the metal and the metal ion is relatively stable within 28 days, the commercialization product has 3 years shelf life. Spinosad in the air is less volatile.
Spinosad in the environment, through a variety of combination ways to degrade, mainly is the light degradation and microbial degradation, eventually become a component of carbon, hydrogen, oxygen, nitrogen and other natural compounds. The half-life of spinosad degraded by soil photolysis is 9 to 10 days, while the half-life of water photolysis is less than 1 day, the half-life of foliar photodegradation is 1.6 to 6 days. In the absence of light, the half-life of spinosad through aerobic soil metabolism is 9 to 17 days. In addition, the leaching property of spinosad is very low, fair use would not pose a threat to groundwater.
Spinosad is a broad-spectrum insecticide, experiments proved that spinosad can effectively control Lepidoptera, Coleoptera and Thysanoptera pests, in addition, it also have a good prevention in some of the large number of swallowed the blade pest species in Orthoptera and Diptera. Activity of spinosad for lepidopteran larvae is significantly greater than the organic phosphorus, carbamate insecticides, be equal to pyrethroid. While spinosyns having a high insecticidal activity, also exhibit low toxicity on predatory insects, to lepidopteran insects, spinosad is one of the highest selectivity compounds that has been found in insecticide. In addition, spinosad for thrips, lice, termites, and many Hymenoptera pests also have good effect.
According to the Chinese pesticide toxicity grading standards, Spinosad is a low-toxicity insecticide. With relatively low toxicity to mammals and birds, to aquatic animals are only slightly moderately toxic. In addition, the chronic toxicological tests to mammalian showed that spinosad no teratogenic, mutagenic, carcinogenic effects or neurotoxicity. The amount and toxicity of spinosad were lower than those currently used grain storage pesticides. Spinosad for many beneficial insects and beneficial organisms have high safety demarcation line, compared with predatory beetles, lacewings and mites, it with less toxic. Compared with the traditional cypermethrin, spinosad showed low insecticidal activity in some important beneficial insects, while in the prevention and control of lepidopteran pests, the activity intensity of spinosad and cypermethrin are usually comparable. Therefore, spinosad is the first choice to do the integrated pest management.
Spinosad as a biological insecticide, both have the characteristics of the security of biological pesticides and the fast-acting effect of chemical synthetic pesticides, there are 73 countries registered applications in more than 250 kinds of crops. Since 1997, the first time appear this product, spinosad was always maintaining the efficiency and safety industrial history. Currently, there are a lot of spinosad products be recommended for use in organic agriculture. Due to spinosad can effectively prevent and control major grain storage pests, as well as no environmental pollution, is considered to be the best agent in the stored grain protectants.
Source:http://www.cospcn.com

Careful used the pregnant women cosmetics



The 30-year-old woman called Miss Zhang who has been pregnant for three months. Recently, Miss Zhang is always puzzled about whether put on makeup or not, because she is doing a sales job in the bank, the external image is very important at ordinary times, and put on makeup also become a habit in her live. But after pregnancy, in order to ensure the safety and health in the pregnancy period, she had to give up putting on makeup, every day after washing face, her face was coated nothing. She felt that since stop using the cosmetics and skin care products, her face was always feel dry, and the skin was worse than before, the external image is greatly reduced. Perhaps, pregnancy is a very happy thing for every woman, but in pregnant period, ladies were because of fearing the cosmetics will affect their unborn fetus, in choosing cosmetics they are more or less have some concerns.
It is understood that many pregnant women, because of fearing the chemical ingredients in cosmetics will affect the fetus, most of them were giving up make-up, also there are a considerable part of pregnant women who pursuing beauty were puzzling about whether put on makeup or not. In this regard, many doctors said that pregnant women should also do well in skin care, because pregnancy is a special time, some pregnant women because of hormonal changes in the body, the skin will be changed, such as lack of nutrition, dry, spot, allergies and so on, if pregnant women were blindly ignored, it will not only because of the appearance changes affect the mood, the skin will be damaged quickly. The doctors believe that pregnant women do not have to be afraid of make-up, instead, can through applying cosmetics or rub some skin care products to spread the tension feeling caused by pregnancy, thus enhance the self-confidence. Buy cosmetics during pregnancy must be choose non-irritating product, better to choose weak acidic products that produced by natural raw materials. In addition, you must stop using the skin care products which containing tretinoin, according to tretinoin manufacturer, this substance is easy to cause birth defects of the baby, especially the whitening, freckle cosmetics contain higher levels of tretinoin.
In view of the particularity of pregnant period, when choosing skin care products, pregnant women can’t not choose those products containing hormones and chemical composition which will be harmful to the fetus, better to choose mild pure plant products. In order to meet this demand, businesses in recent years also accordingly launched a special cosmetic for pregnant women, it was concerned by expectant mothers. Some expectant mothers were suspected the cosmetics which advertised natural plant preparation, mostly of them were not dared to try. It is understood that, under normal circumstances, the cosmetic raw materials are formulated by a variety of chemical components, wherein the deionized water was accounted for the most ratio, depending on the different product types may also be added other ingredients, such as glycerin, white oils, silicone oils, stearic acid, nutrients, flavors and preservatives. In contrast, the natural plant ingredients is only a small part, pure natural plant ingredients can not be made ​​into products. Face on the market, a number of pregnant women cosmetics under the banner of "natural" name, professionals believe that the variety does not have the relevant standards, its ingredients and additives should be made ​​in accordance with the requirements of ordinary products, as for whether their efficacy is significantly, ingredients are really natural is no way to check on, therefore, recommend prospective mothers in the purchase of pregnant women cosmetics must polish their eyes, do not believe the publicity of exaggerating efficacy, pay attention to whether the ingredients contained in products are safe and effective.
Source:http://www.cosprm.com